Ingredients
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Glycerin is a naturally derived humectant—a ingredient that draws moisture from the air into your skin. It's one of the most widely used and well-studied moisturizing agents in skincare, helping skin feel softer and more hydrated.
Benefits
- Attracts and retains moisture in the skin
- Improves skin hydration and softness
- Helps strengthen skin barrier function
- Suitable for most skin types, including sensitive skin
Science: The Cosmetic Ingredient Review Expert Panel concluded glycerin is safe as used in cosmetics across all concentrations. Research shows glycerin effectively improves skin hydration and is well-tolerated with minimal irritation risk. It is also referenced in clinical guidelines for managing inflammatory skin conditions and maintaining skin integrity.
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Sodium hyaluronate is the salt form of hyaluronic acid, a naturally occurring substance found in your skin that acts like a moisture magnet. In skincare products, it absorbs water from the environment and binds it to your skin, helping to hydrate and plump the skin's surface.
Benefits
- Delivers intense hydration to the skin
- Helps reduce the appearance of fine lines by improving skin moisture
- Supports skin barrier function
- Suitable for all skin types, including sensitive and oily skin
Potential concerns
- In very dry climates with low humidity, it may draw moisture from deeper skin layers if not sealed with an occlusive product
- Rare allergic reactions are possible but extremely uncommon
Science: While the provided research focuses on intra-articular injections for joint health (showing good safety and efficacy), hyaluronic acid and its salt form are well-established in dermatology for topical hydration. The molecule's safety profile is well-documented across decades of use in medical and cosmetic applications, with severe adverse reactions being extremely rare.
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Potassium sorbate is a preservative used in skincare products to prevent the growth of mold, yeast, and some bacteria, helping extend shelf life. It's a salt derived from sorbic acid and is commonly used as a gentler alternative to stronger chemical preservatives.
Benefits
- Prevents microbial contamination and mold growth
- Generally considered milder than some other preservatives like benzalkonium chloride
- Allows products to remain effective longer without refrigeration
Potential concerns
- May cause irritation or allergic contact dermatitis in sensitive individuals
- Not suitable for preservative-free formulations
- Limited effectiveness against some bacteria compared to stronger preservatives
Science: Clinical research suggests potassium sorbate is less damaging to delicate tissues than benzalkonium chloride, making it a preferred alternative preservative in sensitive applications like eye products. However, peer-reviewed safety data specific to topical skincare use in the general population is limited.
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Sodium benzoate is a preservative used in skincare products to prevent bacterial and fungal growth, extending shelf life. It's a salt derived from benzoic acid and is one of the most widely used preservatives in cosmetics, skincare, and food products.
Benefits
- Prevents microbial contamination and extends product shelf life
- Generally effective at low concentrations (0.1-0.5%)
- Approved for cosmetic use by major regulatory bodies
Potential concerns
- Can cause allergic contact dermatitis in sensitive individuals; identified as an allergen in medical hand cleansers
- Recent research suggests long-term oral intake may affect bone health and increase osteoporosis risk, though topical skincare exposure is minimal
Science: Sodium benzoate is well-established as a safe preservative in cosmetics at typical use levels. However, emerging research indicates that chronic systemic intake may interfere with bone metabolism through the FGF2/p38/RUNX2 pathway. For topical skincare use, the exposure and absorption are minimal compared to dietary intake, but individuals with known sensitivities should avoid it.
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Propanediol is a lightweight humectant—a molecule that draws water into the skin to keep it hydrated. It's also used in cosmetic formulations as a solvent and preservative booster, helping products stay stable and feel smooth on the skin.
Benefits
- Hydrates and moisturizes the skin
- Improves product texture and spreadability
- Helps preserve formulations naturally
Science: Propanediol can be produced through bio-based fermentation (from glycerol using microorganisms), making it an environmentally friendly alternative to traditional chemical synthesis. It is widely recognized as safe in cosmetic and food applications, with established use as both a humectant and preservative enhancer.
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Chlorella vulgaris extract is a nutrient-rich ingredient derived from a freshwater microalgae. It contains proteins, antioxidants, and other bioactive compounds that may help support skin healing and protect against oxidative damage.
Benefits
- Antioxidant protection (demonstrated at 76% antioxidant activity in research)
- May support skin healing and wound repair processes
- Potential anti-inflammatory properties
Potential concerns
- Limited human clinical data — most evidence comes from animal studies or formulations combining multiple ingredients
- May cause mild irritation in sensitive skin at high concentrations
Science: Research shows chlorella vulgaris extract has measurable antioxidant capacity and supported wound healing in a rat burn model when combined with collagen and silver. However, published data on this ingredient in standalone skincare products for human use is limited, making it difficult to assess efficacy and safety in typical consumer formulations.
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Xanthan gum is a natural thickener derived from fermented bacteria that helps give skincare products a smooth, gel-like texture. It stabilizes formulas and prevents ingredients from separating, while also helping products spread evenly on skin.
Benefits
- Creates smooth, pleasant texture
- Stabilizes emulsions and prevents separation
- Improves product spreadability and application
Science: Xanthan gum is an FDA-approved, anionic polysaccharide with a long history of safe use across food, pharmaceutical, and cosmetic industries since 1969. Its performance as a thickener and stabilizer is well-established in scientific literature, with no notable skin irritation concerns reported.
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Gluconolactone is a gentle exfoliating acid that belongs to the polyhydroxy acid (PHA) family. It works by removing dead skin cells from the surface and is known for being less irritating than stronger acids, making it suitable for sensitive skin types.
Benefits
- Gentle exfoliation that removes dead skin cells
- Increases skin hydration and strengthens the skin barrier
- Reduces sebum production and helps balance oily skin
- May help reduce inflammation and support skin with sensitivity or irritation
Potential concerns
- May cause mild irritation, redness, or dryness when first introduced, especially in sensitive skin
- Can increase sun sensitivity — sunscreen is recommended during use
Science: Recent research shows gluconolactone effectively improves skin hydration, reduces sebum, and strengthens the skin barrier when used in chemical peels. Emerging evidence suggests it may have immune-regulating properties that could help calm inflammatory skin conditions, though this research is still in early stages.
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Analysis not yet available for this ingredient.
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Ascorbyl palmitate is a stabilized form of vitamin C (ascorbic acid) that's designed to be more shelf-stable and easier to formulate into skincare products than pure vitamin C. It works as an antioxidant to help protect skin from environmental damage and may support anti-aging benefits.
Benefits
- Antioxidant protection against free radicals
- May help reduce appearance of fine lines and support skin firmness
- Can help even out skin tone and reduce hyperpigmentation
- More stable formulation option compared to L-ascorbic acid
Potential concerns
- Less potent than pure L-ascorbic acid at the same concentration
- Penetration into deeper skin layers is limited without specialized delivery systems
- May cause mild irritation in sensitive skin at higher concentrations
Science: Recent research (2024) shows that ascorbyl palmitate has good antioxidant and anti-aging properties similar to L-ascorbic acid. When encapsulated in liposomes, skin penetration improved significantly (1.2–1.3 fold increase), suggesting that standard formulations may have limited effectiveness unless specifically optimized for absorption.
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Hydrolyzed algin is a thickening and moisture-binding ingredient derived from brown seaweed. It forms a lightweight film on the skin to help retain hydration and improve product texture.
Benefits
- Hydration and moisture retention
- Improved product texture and spreadability
- Skin-soothing properties
Science: Limited peer-reviewed data available for this ingredient. Algin derivatives are well-established as safe, non-toxic ingredients in cosmetics with a long history of use in skincare formulations.
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Cetearyl glucoside is a natural, plant-derived emulsifier made from fatty alcohols and glucose. It helps bind water and oil together in skincare products to create smooth, stable creams and lotions.
Benefits
- Creates stable emulsions with a smooth texture
- Naturally derived and considered skin-friendly
- Gentle alternative to synthetic emulsifiers
Potential concerns
- Rare cases of allergic contact dermatitis reported in sensitive individuals
- May affect how active ingredients penetrate the skin depending on formulation
Science: Research shows cetearyl glucoside forms stable emulsions with complex internal structures that can influence how sunscreen and other actives penetrate skin. One case of allergic contact dermatitis was documented, though such reactions appear uncommon.
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Dihydroxyacetone (DHA) is a 3-carbon sugar approved by the FDA as a color additive for sunless tanning products. When applied to skin, it reacts with proteins in the outer layer to produce a temporary brown tan-like color that develops over a few hours.
Benefits
- Creates a tan appearance without sun exposure
- Temporary effect that washes off with soap and water
- Allows customization of tan depth depending on product concentration
Potential concerns
- Should not contact eyes, lips, or mucous membranes
- Inhalation of spray-tan mist is not FDA-approved and should be avoided
- May cause streaking or uneven coloring if not applied evenly
Science: DHA has been used safely in topical tanning products since the 1960s. It works by binding to free amino groups in skin proteins, particularly arginine, to create the brown color. Current research suggests DHA staining may have diagnostic applications in dermatology for identifying skin lesions.
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Guar gum is a natural thickening ingredient derived from guar beans. In skincare products, it creates a smooth texture and helps bind ingredients together, making creams and lotions easier to apply and more pleasant to use.
Benefits
- Creates smooth, spreadable texture
- Helps stabilize product consistency
- Gentle thickening without heavy feel
Science: Guar gum is widely used in cosmetics and has a strong safety history with regulatory approval across major markets. Limited peer-reviewed data available specifically on guar gum in skincare, but extensive safety data exists from food and cosmetic industries showing no significant irritation or sensitization concerns at typical use levels.
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Heptyl Undecylenate is a synthetic ester derived from undecylenic acid, a fatty acid known for antimicrobial properties. It functions primarily as a preservative and antimicrobial agent in skincare formulations, helping prevent bacterial and fungal growth.
Benefits
- Antimicrobial and preservative function
- Helps extend product shelf life
- May support skin barrier health due to fatty acid origin
Science: Limited peer-reviewed data available for this ingredient. Undecylenic acid and its derivatives have established antimicrobial activity, but specific safety and efficacy studies on heptyl undecylenate in cosmetics are scarce.
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Polyglyceryl-4 Caprate is an emulsifier and solubilizer derived from glycerin and coconut oil. It helps blend water and oil-based ingredients together in skincare formulas, and can improve the delivery of active compounds into the skin.
Benefits
- Helps stabilize product texture and consistency
- Improves absorption and skin penetration of other active ingredients
- Allows water-insoluble beneficial compounds to be used in skincare products
Science: Research demonstrates that polyglyceryl-4 caprate can effectively encapsulate and stabilize natural bioactive compounds (such as α-bisabolol) in nanoparticle form, improving their stability in aqueous products and enabling their use in cosmetics. The ingredient itself showed good biocompatibility in laboratory cell studies.
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