Ingredients
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Dimethicone is a silicone-based ingredient that forms a smooth, protective layer on your skin. It helps lock in moisture, creates a soft feel, and is commonly used in moisturizers and primers to improve product texture and skin hydration.
Benefits
- Improves skin hydration by creating a moisture-barrier layer
- Provides a smooth, silky feel to products and on skin
- Well-tolerated by sensitive and atopic (eczema-prone) skin
- Non-greasy alternative to heavier oils
Science: Clinical studies demonstrate dimethicone is safe and well-tolerated in children with atopic dermatitis from 12 months of age. Research shows moisturizers containing dimethicone effectively improve skin hydration in mild-to-moderate atopic dermatitis patients over 14 days.
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Glycerin is a naturally derived humectant—a ingredient that draws moisture from the air into your skin. It's one of the most widely used and well-studied moisturizing agents in skincare, helping skin feel softer and more hydrated.
Benefits
- Attracts and retains moisture in the skin
- Improves skin hydration and softness
- Helps strengthen skin barrier function
- Suitable for most skin types, including sensitive skin
Science: The Cosmetic Ingredient Review Expert Panel concluded glycerin is safe as used in cosmetics across all concentrations. Research shows glycerin effectively improves skin hydration and is well-tolerated with minimal irritation risk. It is also referenced in clinical guidelines for managing inflammatory skin conditions and maintaining skin integrity.
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Caffeine is a natural alkaloid compound that penetrates the skin barrier and is commonly used in skincare products, typically at 3% concentration. It works by stimulating blood flow, reducing puffiness, and protecting skin cells from damage caused by free radicals and UV exposure.
Benefits
- Reduces under-eye puffiness and swelling by improving blood circulation
- Provides antioxidant protection against UV damage and premature aging
- May help break down fat cells and improve the appearance of cellulite
- Activates cellular repair processes that protect against oxidative stress and aging
Potential concerns
- May cause mild irritation or sensitivity in individuals with caffeine sensitivity
- Can cause temporary redness or tingling when applied topically
- Limited evidence for dramatic anti-cellulite results in real-world use
Science: Research shows caffeine effectively penetrates skin and activates autophagy (cellular cleanup) to combat oxidative stress and cellular aging, particularly from UV exposure. Studies demonstrate it inhibits fat accumulation and improves microcirculation, though most evidence comes from controlled lab and animal studies rather than large human trials.
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Sodium hyaluronate is the salt form of hyaluronic acid, a naturally occurring substance found in your skin that acts like a moisture magnet. In skincare products, it absorbs water from the environment and binds it to your skin, helping to hydrate and plump the skin's surface.
Benefits
- Delivers intense hydration to the skin
- Helps reduce the appearance of fine lines by improving skin moisture
- Supports skin barrier function
- Suitable for all skin types, including sensitive and oily skin
Potential concerns
- In very dry climates with low humidity, it may draw moisture from deeper skin layers if not sealed with an occlusive product
- Rare allergic reactions are possible but extremely uncommon
Science: While the provided research focuses on intra-articular injections for joint health (showing good safety and efficacy), hyaluronic acid and its salt form are well-established in dermatology for topical hydration. The molecule's safety profile is well-documented across decades of use in medical and cosmetic applications, with severe adverse reactions being extremely rare.
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Caprylyl glycol is a preservative and skin-conditioning ingredient derived from coconut oil. It helps prevent bacterial and mold growth in skincare products while also providing mild hydrating and humectant benefits to the skin.
Benefits
- Helps preserve product freshness and prevent contamination
- Provides gentle humectant properties to help retain skin moisture
- Often used as a gentler alternative to traditional preservatives
Potential concerns
- Rare cases of allergic contact dermatitis have been reported in sensitive individuals
- May cause irritation in those with known sensitivity to glycols
Science: A 200-subject repeat patch test study found no delayed hypersensitivity reactions to caprylyl glycol at typical use concentrations. However, isolated case reports of allergic contact dermatitis exist, suggesting it can act as an allergen in susceptible individuals. It is widely used in infant and sensitive-skin formulations as a preservative alternative.
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This is a thickening and stabilizing agent that helps give skincare products their texture and consistency. It works by absorbing water and forming a gel-like network, making products feel smooth and creamy on the skin without leaving a greasy residue.
Benefits
- Creates smooth, pleasant product texture
- Helps stabilize emulsions and prevent separation
- Allows for lightweight formulations that don't feel heavy
Science: Limited peer-reviewed data available for this ingredient. It is widely used in cosmetics and generally recognized as safe by regulatory bodies including the CosIng database and is approved for use in the EU and US.
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Citric acid is a naturally occurring organic acid commonly used in skincare products as an exfoliant and pH balancer. It belongs to a group of ingredients called alpha-hydroxy acids (AHAs) that help remove dead skin cells from the surface.
Benefits
- Gentle exfoliation to improve skin texture and appearance
- Helps reduce the appearance of keratosis and acne
- Balances product pH to maintain skin compatibility
Potential concerns
- Can cause irritation, redness, or sensitivity in some users, especially with prolonged or frequent use
- May increase sun sensitivity — sunscreen use is recommended when using AHA products
- Not suitable for very sensitive or compromised skin without caution
Science: Citric acid is an established AHA used in cosmetics for superficial peeling and skin appearance improvement, though research emphasizes that caution should be exercised due to potential adverse reactions. It is widely produced industrially and well-established in skincare formulations.
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Potassium sorbate is a preservative used in skincare products to prevent the growth of mold, yeast, and some bacteria, helping extend shelf life. It's a salt derived from sorbic acid and is commonly used as a gentler alternative to stronger chemical preservatives.
Benefits
- Prevents microbial contamination and mold growth
- Generally considered milder than some other preservatives like benzalkonium chloride
- Allows products to remain effective longer without refrigeration
Potential concerns
- May cause irritation or allergic contact dermatitis in sensitive individuals
- Not suitable for preservative-free formulations
- Limited effectiveness against some bacteria compared to stronger preservatives
Science: Clinical research suggests potassium sorbate is less damaging to delicate tissues than benzalkonium chloride, making it a preferred alternative preservative in sensitive applications like eye products. However, peer-reviewed safety data specific to topical skincare use in the general population is limited.
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Sodium benzoate is a preservative used in skincare products to prevent bacterial and fungal growth, extending shelf life. It's a salt derived from benzoic acid and is one of the most widely used preservatives in cosmetics, skincare, and food products.
Benefits
- Prevents microbial contamination and extends product shelf life
- Generally effective at low concentrations (0.1-0.5%)
- Approved for cosmetic use by major regulatory bodies
Potential concerns
- Can cause allergic contact dermatitis in sensitive individuals; identified as an allergen in medical hand cleansers
- Recent research suggests long-term oral intake may affect bone health and increase osteoporosis risk, though topical skincare exposure is minimal
Science: Sodium benzoate is well-established as a safe preservative in cosmetics at typical use levels. However, emerging research indicates that chronic systemic intake may interfere with bone metabolism through the FGF2/p38/RUNX2 pathway. For topical skincare use, the exposure and absorption are minimal compared to dietary intake, but individuals with known sensitivities should avoid it.
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Phenoxyethanol is a preservative that prevents bacteria, yeast, and mold from growing in skincare products, helping them stay fresh and safe to use. It has been used safely in cosmetics for decades and is effective at very low concentrations.
Benefits
- Prevents microbial contamination and product spoilage
- Broad-spectrum antimicrobial activity against bacteria and yeast
- Minimal impact on beneficial skin bacteria when used at approved levels
Potential concerns
- Rare allergic contact dermatitis in sensitive individuals
- May cause irritation if used in products at concentrations above 1%
Science: The European Scientific Committee on Consumer Safety considers phenoxyethanol safe for all consumers, including children, at concentrations up to 1%. Adverse effects observed in animal studies required exposure levels approximately 200 times higher than those in cosmetic products, and it is classified as one of the most well-tolerated preservatives in cosmetics.
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Pentylene glycol is a lightweight humectant—a ingredient that draws water into the skin to improve hydration and texture. It's commonly used in serums, sunscreens, and moisturizers as a preservative booster and skin-conditioning agent.
Benefits
- Improves skin hydration by attracting moisture
- Lightweight feel, absorbs quickly without heaviness
- Helps preserve product stability and extends shelf life
Potential concerns
- Rare contact allergy reported in sensitive individuals
- Emerging evidence suggests it may be an uncommon cosmetic allergen—if you have sensitive or reactive skin, patch test first
Science: Safety studies show a high margin of safety at standard use levels (87–671 in adults), with minimal skin penetration due to the ingredient's volatility. However, recent dermatological reports flag pentylene glycol as an emerging contact allergen in some individuals, warranting attention for those with sensitive skin.
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Tocopherol is a form of vitamin E, a fat-soluble antioxidant that protects skin from damage caused by free radicals and oxidative stress. It helps maintain skin's natural barrier function and is commonly used in skincare products to prevent premature aging and support overall skin health.
Benefits
- Protects skin from free radical damage and oxidative stress
- Supports skin barrier function and moisture retention
- May help reduce signs of aging caused by UV exposure and environmental damage
- Works as a lipid antioxidant to prevent degradation of skin oils
Science: Tocopherol (α-tocopherol) is recognized in peer-reviewed research as a key endogenous defense mechanism against oxidative stress in aging skin, particularly from UV-induced damage. Studies confirm it functions as a lipid-soluble antioxidant capable of preventing lipid peroxidation, with established efficacy in cosmetic and therapeutic applications.
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Ethylhexylglycerin is a preservative and antimicrobial ingredient used to prevent bacterial growth and extend shelf life in skincare products. It's a multifunctional ingredient that helps keep formulations stable and free from contamination.
Benefits
- Prevents bacterial contamination in products
- Helps extend product shelf life
- Works synergistically with other preservatives for enhanced protection
Potential concerns
- May not be effective against all bacterial species (notably some Pseudomonas aeruginosa strains)
- Preservative-related sensitization possible in sensitive individuals, though uncommon
Science: Research shows ethylhexylglycerin has broad antimicrobial activity against many common cosmetic contaminants, though effectiveness varies by bacterial species. Studies demonstrate it can work synergistically with other preservative components to enhance biofilm inhibition.
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Sodium Hydroxide is a strong alkaline chemical used in skincare products primarily as a pH buffer to neutralize acids and adjust the product's pH to safe levels for skin. It is not an active skincare ingredient and appears only in trace amounts in finished products.
Potential concerns
- In concentrated form, sodium hydroxide is caustic and can cause severe chemical burns; however, in cosmetic products it is diluted and pH-buffered to safe levels
- Undiluted or highly concentrated sodium hydroxide should never contact skin directly
Science: The provided research discusses sodium hydroxide only in a specialized medical context (10% solution for surgical cauterization of ingrown toenails), which is not relevant to cosmetic skincare use. In properly formulated skincare products, sodium hydroxide is used in minimal concentrations solely for pH adjustment and is considered safe by regulatory bodies including the FDA and EU.
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Xanthan gum is a natural thickener derived from fermented bacteria that helps give skincare products a smooth, gel-like texture. It stabilizes formulas and prevents ingredients from separating, while also helping products spread evenly on skin.
Benefits
- Creates smooth, pleasant texture
- Stabilizes emulsions and prevents separation
- Improves product spreadability and application
Science: Xanthan gum is an FDA-approved, anionic polysaccharide with a long history of safe use across food, pharmaceutical, and cosmetic industries since 1969. Its performance as a thickener and stabilizer is well-established in scientific literature, with no notable skin irritation concerns reported.
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Disodium EDTA is a chelating agent that binds to metals and minerals in skincare formulations. It helps stabilize products, prevent discoloration, and improve texture by controlling how other ingredients behave in the formula.
Benefits
- Stabilizes skincare formulations and extends shelf life
- Prevents oxidation and discoloration of products
- Improves product texture and consistency
Potential concerns
- May increase skin penetration of other ingredients in the formula
- Not absorbed through skin under normal use, but inhalation from sprays should be minimized
- Can cause irritation at high concentrations, though typical use levels (under 2%) are considered safe
Science: The Cosmetic Ingredient Review Expert Panel confirmed in 2023 that disodium EDTA is safe at typical cosmetic use concentrations (under 2%). Research shows it is not absorbed through intact skin, though it may affect how other ingredients penetrate skin due to its mineral-binding properties. No carcinogenic effects have been identified.
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Analysis not yet available for this ingredient.
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Analysis not yet available for this ingredient.
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Citral is a naturally-derived fragrance compound found in citrus essential oils and lemongrass. It's used in skincare products primarily to provide a fresh, lemony scent while also contributing mild preservative and skin-conditioning properties.
Benefits
- Provides natural fragrance
- May support skin renewal through TRPV3 receptor activation
- Acts as a natural preservative agent
- Derived from plant sources
Potential concerns
- Can cause skin sensitization or irritation in sensitive individuals
- May trigger photosensitivity reactions when combined with sun exposure
- Known allergen for some people; fragrance-related contact dermatitis possible
- Essential oil components can be irritating at high concentrations
Science: Recent research (2025) suggests citral and plant essential oils may activate TRPV3 receptors involved in skin renewal, though human efficacy data is limited. Citral is widely recognized as a fragrance ingredient in cosmetics, but like most essential oil components, carries potential for sensitization in vulnerable individuals.
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Limonene is a natural fragrance compound found in citrus oils and other plants. It's used in skincare products primarily to provide a fresh, lemon-like scent and may have mild preservative properties.
Benefits
- Provides natural fragrance
- May help preserve products
- Derived from natural plant sources
Potential concerns
- Can cause skin irritation or allergic contact dermatitis in sensitive individuals
- May oxidize over time, potentially becoming more irritating
- Inhalation of high concentrations may pose concerns; use caution with products prone to aerosolization
Science: Limonene is a widely used fragrance component in cosmetics derived from essential oils. However, research indicates that monoterpenes like limonene can exhibit hepatotoxic properties and penetrate skin readily; while cosmetic concentrations are typically low, individuals with sensitive skin or fragrance allergies should exercise caution.
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Linalool is a naturally occurring fragrant compound found in lavender and other plants, commonly used in skincare products for its pleasant scent. It's a volatile component of essential oils and plant extracts that contributes to the aromatic profile of formulations.
Benefits
- Provides natural fragrance to skincare products
- Derived from plants traditionally associated with calming and relaxation properties
- Part of essential oil blends used in aromatherapy applications
Potential concerns
- May cause skin irritation or allergic contact dermatitis in sensitive individuals
- Can oxidize when exposed to air, potentially creating irritant byproducts
- Lavender extracts containing linalool have estrogenic and antiandrogenic properties — topical application near the breast should be avoided
Science: Lavender, which contains linalool as a major compound, is recognized as generally safe (GRAS) by the FDA. However, limited peer-reviewed safety data exists specifically for linalool in topical skincare formulations, and individual sensitivity varies. Caution is warranted for prolonged or concentrated use, particularly in sensitive populations.
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Ascorbyl Glucoside is a stable form of vitamin C that's been chemically modified to last longer in skincare products. Once absorbed into the skin, your body converts it into active vitamin C, which helps brighten skin tone, reduce the appearance of dark spots, and support overall skin health.
Benefits
- Helps fade dark spots and uneven pigmentation (solar lentigos)
- Brightens overall skin tone and improves radiance
- More stable than standard vitamin C, so it stays effective longer in products
- Antioxidant protection against environmental damage
Science: Clinical research demonstrates that ascorbyl glucoside-arginine complex significantly reduced pigmentation in sun spots after 24 weeks of twice-daily use, with visible lightening effects and no reported adverse effects or unwanted skin bleaching. The ingredient is well-tolerated and considered a safe, effective alternative to less stable vitamin C forms.
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Alcohol Denat is denatured ethanol (regular alcohol) that has been made undrinkable by adding bitter-tasting substances. It's used in skincare products as a solvent and preservative to help dissolve other ingredients and extend shelf life.
Benefits
- Helps dissolve and blend skincare ingredients together
- Provides preservative function to prevent microbial growth
- Gives products a lightweight, fast-absorbing texture
Potential concerns
- Can be drying or irritating to sensitive skin with repeated use
- May cause stinging if applied to broken skin or open wounds
- High concentrations may trigger irritation in those with sensitive or reactive skin
Science: The Cosmetic Ingredient Review Expert Panel concluded that Alcohol Denat and its various forms are safe as used in cosmetics. Denaturants added to prevent accidental ingestion (such as Denatonium Benzoate) show low systemic absorption and minimal irritation at typical skincare concentrations.
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Ethylhexyl salicylate is a UV filter ingredient used in sunscreens to absorb ultraviolet (UV) rays and protect skin from sun damage. It's an organic compound that helps prevent sunburn and photoaging by converting UV radiation into heat on the skin's surface.
Benefits
- Provides UVB sun protection as part of sunscreen formulations
- Helps prevent sunburn and sun-related skin damage
- Commonly used in combination with other UV filters for broader protection
Potential concerns
- May cause skin irritation or allergic contact dermatitis in sensitive individuals
- Limited individual safety data; typically assessed as part of multi-filter sunscreen formulations
Science: A 2024 clinical study found that ethylhexyl salicylate in a sunscreen formulation did not induce facial skin dysbiosis or negatively affect acne-related bacteria over 10 days of use, suggesting it is unlikely to trigger acne through microbiome disruption. However, limited peer-reviewed data exists specifically evaluating this ingredient in isolation.
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Ceramide NP is a naturally-derived lipid that mimics ceramides found in healthy skin. It works to repair and strengthen your skin's protective barrier, helping it retain moisture and resist irritation.
Benefits
- Restores skin barrier function and structural integrity
- Reduces trans-epidermal water loss (helps skin stay hydrated)
- Strengthens skin's natural defense against irritants and environmental stressors
Science: Recent research demonstrates that Ceramide NP effectively recovers damaged skin barrier function and can be formulated into advanced delivery systems (like ethosomes) to enhance skin absorption. Studies show it meaningfully lowers water loss while restoring epidermis structure in compromised skin.
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Aloe Barbadensis Leaf Juice is the clear gel extracted from the inner part of the aloe vera leaf. In skincare, it functions as a skin-conditioning agent known for its soothing and hydrating properties, and is typically used at low concentrations (usually under 1%).
Benefits
- Soothing and anti-inflammatory properties
- Hydrating and skin-conditioning
- Antimicrobial and wound-healing support
Potential concerns
- Whole leaf aloe (including latex) contains anthraquinones that can cause photosensitivity and irritation; reputable products use only the inner gel
- High oral doses in animal studies showed reproductive toxicity and developmental effects; topical use in cosmetics at low concentrations is considered safe
- Potential for allergic contact dermatitis in sensitive individuals
Science: A 2007 safety review by the Cosmetic Ingredient Review panel concluded aloe-derived ingredients are safe for cosmetic use when the phototoxic anthraquinone content is limited to 50 ppm or lower and concentrations remain at 1% or less. The inner gel (polysaccharides) is well-tolerated topically, though oral studies at high doses showed concerns unrelated to typical skincare application.
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Sodium polyacrylate is a synthetic polymer that absorbs and holds water, creating a gel-like texture. In skincare, it's used as a thickener and moisture-retention agent to improve product consistency and help keep skin hydrated.
Benefits
- Absorbs and retains moisture to support skin hydration
- Thickens product texture for better application and feel
- Creates a smooth, spreadable consistency in formulations
Science: Contact dermatitis research involving multiple UK hospital dermatology centres found that sensitisation to sodium polyacrylate is rare, indicating excellent safety for topical skincare use. The ingredient has also been studied for advanced biomedical applications including wearable sensors, demonstrating its biocompatibility.
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Menthyl Lactate is a cooling agent derived from menthol and lactic acid. It provides a refreshing, minty sensation on the skin without the intensity of pure menthol, making it popular in products designed to soothe and invigorate tired or irritated skin.
Benefits
- Provides a cooling, refreshing sensation
- Gentler cooling effect compared to pure menthol
- May help soothe minor skin irritation
Potential concerns
- Can cause mild tingling or irritation in sensitive skin
- May trigger reactions in those sensitive to mint or menthol derivatives
Science: Limited peer-reviewed data available for this ingredient. Safety and sensory profile are inferred from its chemical structure as a menthol derivative combined with lactic acid, both established cosmetic ingredients with known safety records.
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Homosalate is a chemical UV filter that absorbs UVB rays to protect skin from sun damage. It's commonly used in sunscreens and is often combined with other UV-blocking ingredients for broader protection.
Benefits
- Absorbs UVB radiation to help prevent sunburn
- Lightweight and works well in various sunscreen formulations
- Allows for flexible product formats (lotions, sprays, etc.)
Potential concerns
- Systemic absorption occurs—research shows it enters the bloodstream at levels exceeding FDA's 0.5 ng/mL threshold after a single application
- Long-term effects of systemic absorption are not yet fully understood
- May cause skin irritation or allergic contact dermatitis in sensitive individuals
Science: A 2020 FDA-led clinical trial found that homosalate, along with five other common sunscreen actives, is systemically absorbed and exceeds the FDA's recommended safety threshold (0.5 ng/mL) after a single application. While this absorption is documented, the clinical significance and long-term health implications remain under investigation.
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Octocrylene is an organic UV filter that absorbs ultraviolet radiation, primarily UVB and short-wavelength UVA rays. It's commonly used in sunscreens and other cosmetic products to provide sun protection and prevent UV damage to skin and product formulations.
Benefits
- Provides UVB and short-wavelength UVA sun protection
- Works synergistically with other UV filters (notably stabilizes avobenzone)
- Feels pleasant on skin, which encourages regular sunscreen use
- Helps prevent skin cancer and UV-induced skin damage
Potential concerns
- Potential allergic or photoallergic reactions in sensitive individuals
- Concerns about possible endocrine system effects (currently under ongoing regulatory assessment)
- Not a complete broad-spectrum protector on its own (limited UVA coverage)
Science: Recent research indicates octocrylene is stable and provides UV protection with minimal adverse effects compared to other organic filters like oxybenzone. However, potential endocrine concerns have been raised and the ingredient remains under continuous safety review by regulatory agencies including the European Chemical Agency.
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Hydrolyzed soy protein is soy protein that has been broken down into smaller pieces to make it easier for skin to absorb. It's used in skincare to help condition and moisturize the skin.
Benefits
- May improve skin hydration and moisture retention
- Can help soften and smooth skin texture
- Provides amino acids that support skin health
Potential concerns
- People with soy allergies or sensitivities may experience irritation or allergic reactions
- May cause contact dermatitis in sensitive individuals
Science: Research in dogs with soy protein hypersensitivity shows that hydrolyzed soy protein triggers significantly fewer allergic reactions compared to native (non-broken down) soy protein, suggesting the hydrolysis process reduces allergenic properties. Limited peer-reviewed data is available on topical use in humans, though the reduced allergenicity of the hydrolyzed form is a positive indicator for sensitive skin.
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Butyl methoxydibenzoylmethane, commonly known as avobenzone, is a UV filter used in sunscreens to protect skin from UVA rays (the sun's aging rays). It absorbs UV radiation and converts it into harmless heat, helping prevent sun damage and premature aging.
Benefits
- Broad-spectrum UVA protection against sun damage and premature skin aging
- Low skin absorption—most of the ingredient stays on the surface rather than penetrating deeply
- Long history of safe use in over-the-counter sunscreen products
Potential concerns
- Rare photoallergy reported in clinical case studies (sensitivity to sunlight triggered by the ingredient)
- May cause mild dermal irritation in sensitive individuals, though uncommon
Science: A 2025 comprehensive toxicology review found avobenzone has a suitable safety profile with no clear markers of toxicity. Clinical studies confirm low skin absorption (≤0.59% of applied dose), and safety margins exceed 100-fold when used at permitted levels (up to 3%). No evidence of carcinogenicity, genotoxicity, or hormonal disruption was identified.
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This is a film-forming polymer that combines silicone and acrylic components. It creates a smooth, flexible coating on the skin's surface to improve texture, provide a soft-focus effect, and help other ingredients stay on the skin longer.
Benefits
- Smooths skin texture and minimizes the appearance of pores and fine lines
- Creates a silky, comfortable feel on the skin
- Helps create a matte or satin finish in products
Science: Limited peer-reviewed data available for this ingredient. It is widely used in cosmetics as a film-forming agent and is generally recognized as safe by regulatory bodies including the FDA and EU cosmetics regulations.
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Analysis not yet available for this ingredient.
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