Ingredients
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Butylene glycol is a humectant—a type of ingredient that draws water into the skin and helps it stay hydrated. It's a small, lightweight molecule commonly used in moisturizers to improve hydration without leaving a heavy feel on the skin.
Benefits
- Increases skin hydration and moisture retention
- Lightweight and absorbs quickly
- Helps other active ingredients penetrate the skin more effectively
Science: Research demonstrates that butylene glycol, when combined with other humectants (like glycerin and hyaluronic acid) and occlusive ingredients in moisturizers, significantly improves skin hydration in both healthy skin and compromised skin conditions such as atopic dermatitis. It is recognized as a safe, effective humectant in dermatological formulations.
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Glycerin is a naturally derived humectant—a ingredient that draws moisture from the air into your skin. It's one of the most widely used and well-studied moisturizing agents in skincare, helping skin feel softer and more hydrated.
Benefits
- Attracts and retains moisture in the skin
- Improves skin hydration and softness
- Helps strengthen skin barrier function
- Suitable for most skin types, including sensitive skin
Science: The Cosmetic Ingredient Review Expert Panel concluded glycerin is safe as used in cosmetics across all concentrations. Research shows glycerin effectively improves skin hydration and is well-tolerated with minimal irritation risk. It is also referenced in clinical guidelines for managing inflammatory skin conditions and maintaining skin integrity.
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Tocopherol is a form of vitamin E, a fat-soluble antioxidant that protects skin from damage caused by free radicals and oxidative stress. It helps maintain skin's natural barrier function and is commonly used in skincare products to prevent premature aging and support overall skin health.
Benefits
- Protects skin from free radical damage and oxidative stress
- Supports skin barrier function and moisture retention
- May help reduce signs of aging caused by UV exposure and environmental damage
- Works as a lipid antioxidant to prevent degradation of skin oils
Science: Tocopherol (α-tocopherol) is recognized in peer-reviewed research as a key endogenous defense mechanism against oxidative stress in aging skin, particularly from UV-induced damage. Studies confirm it functions as a lipid-soluble antioxidant capable of preventing lipid peroxidation, with established efficacy in cosmetic and therapeutic applications.
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Ethylhexylglycerin is a preservative and antimicrobial ingredient used to prevent bacterial growth and extend shelf life in skincare products. It's a multifunctional ingredient that helps keep formulations stable and free from contamination.
Benefits
- Prevents bacterial contamination in products
- Helps extend product shelf life
- Works synergistically with other preservatives for enhanced protection
Potential concerns
- May not be effective against all bacterial species (notably some Pseudomonas aeruginosa strains)
- Preservative-related sensitization possible in sensitive individuals, though uncommon
Science: Research shows ethylhexylglycerin has broad antimicrobial activity against many common cosmetic contaminants, though effectiveness varies by bacterial species. Studies demonstrate it can work synergistically with other preservative components to enhance biofilm inhibition.
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Cellulose gum (also called carboxymethyl cellulose or CMC) is a natural thickener derived from plant cellulose. In skincare products, it creates a smooth texture, helps formulas spread evenly, and can form a light protective film on the skin's surface.
Benefits
- Improves product texture and spreadability
- Provides light film-forming properties for a polished feel
- Generally well-tolerated by most skin types
- Natural origin and biodegradable
Potential concerns
- May occasionally cause irritation in very sensitive skin
- Can feel sticky or heavy at high concentrations
Science: Cellulose gum is recognized as a safe, biocompatible polysaccharide widely used across food, cosmetic, and pharmaceutical industries. No significant safety concerns were identified in the available literature for cosmetic applications.
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2-Hexanediol is a humectant and preservative booster commonly used in skincare products to help retain moisture and extend shelf life. It works by drawing water into the skin while also enhancing the effectiveness of other preservatives, allowing brands to use lower amounts of traditional preservatives.
Benefits
- Hydrates and moisturizes skin by drawing in water
- Helps preserve products with lower preservative levels
- Works synergistically with other skincare ingredients like niacinamide
Potential concerns
- May cause cell viability concerns at concentrations above 1.0% in laboratory studies
- Limited real-world safety data in humans at typical skincare concentrations (usually 2-5%)
- Potential environmental concern if released into water systems
Science: While 2-hexanediol is widely used as a preservative substitute for parabens, recent cytotoxicity studies raise questions about safety at concentrations commonly found in skincare products (>2%). However, these findings are from laboratory cell studies and may not directly translate to human skin application. Further human safety studies are needed to confirm real-world risk.
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Stearic acid is a naturally occurring fatty acid commonly derived from plant or animal sources. In skincare products, it functions as an emollient and emulsifier, helping to soften skin, improve product texture, and stabilize formulations by allowing oil and water to mix together.
Benefits
- Softens and moisturizes skin by forming a protective barrier
- Improves product texture and stability
- Helps other active ingredients penetrate the skin more effectively
Potential concerns
- May cause mild irritation or sensitivity in people with very sensitive skin
- Can leave a slight waxy residue if used in high concentrations
Science: Research indicates stearic acid acts as a permeation enhancer, potentially improving how active ingredients cross the skin barrier. It is well-established in cosmetic formulation design and has a strong safety history in topical products.
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Myristic acid is a naturally occurring saturated fatty acid found in common foods like nutmeg and coconut oil. In skincare, it functions as an emollient and texturizing agent that helps soften and condition the skin.
Benefits
- Skin-conditioning and emollient properties
- May help reduce skin inflammation
- Naturally derived fatty acid with established safety history
Potential concerns
- May cause irritation to skin and eyes in pure, concentrated form
- Limited specific safety data for topical skincare use in humans
Science: Myristic acid has a strong safety record as a food ingredient with low acute toxicity. Recent research suggests it may have anti-inflammatory and pain-reducing properties when applied to skin. However, most peer-reviewed safety data comes from food applications rather than cosmetic use.
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Sodium phytate is a naturally derived ingredient that acts as a chelating agent, binding to minerals and metals on the skin's surface. In skincare, it's primarily studied for its potential brightening and clarifying properties, though research in this area remains limited.
Benefits
- May help brighten skin appearance
- Potential mild exfoliating or clarifying effect
- Naturally derived ingredient
Potential concerns
- Very limited safety data in skincare applications
- Chelating agents can potentially disrupt skin barrier minerals if used excessively
- Most research focuses on dental use rather than facial skincare
Science: Available research on sodium phytate focuses primarily on dental whitening toothpaste rather than skincare products. One 2025 clinical trial showed modest whitening effects in toothpaste formulations over 3-4 weeks, but efficacy plateaued. Peer-reviewed safety and efficacy data specifically for facial skincare use is limited.
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Methylpropanediol is a lightweight humectant and preservative booster commonly used in skincare formulations. It helps products stay stable while drawing moisture into the skin, making it useful in serums, moisturizers, and other hydrating products.
Benefits
- Humectant that helps skin retain moisture
- Enhances the preservative system in formulations
- Light texture that absorbs easily without greasiness
Science: Research confirms methylpropanediol functions effectively as a polyol solvent in cosmetic formulations and is recognized as a safe alternative preservative booster. The ingredient has been validated in quality control testing of commercial skincare products with good safety margins.
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Jojoba seed oil is a natural oil extracted from jojoba plant seeds that closely mimics the skin's natural sebum. It's commonly used in skincare to moisturize, balance oil production, and improve skin texture without leaving a heavy residue.
Benefits
- Lightweight moisturization
- Helps balance oily and dry skin
- Rich in vitamin E and antioxidants
- Generally non-comedogenic (unlikely to clog pores)
Potential concerns
- Rare allergic reactions in sensitive individuals
- May not be suitable for very acne-prone skin in high concentrations
Science: Jojoba oil has a long history of safe use in cosmetics and is well-tolerated by most skin types. Limited peer-reviewed data available for this specific ingredient, but extensive industry experience and anecdotal evidence support its safety and efficacy as a natural moisturizer.
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Potassium hydroxide is a strong alkaline chemical used in skincare products primarily as a pH buffer and emulsifier to neutralize acids and help blend oil and water-based ingredients. In cosmetics, it's used in very small amounts to adjust and maintain product pH.
Benefits
- pH adjustment and stabilization
- Helps create stable emulsions in creams and lotions
- Enables mixing of incompatible ingredients
Potential concerns
- Can cause skin irritation or chemical burns if used at high concentrations
- May disrupt skin's natural pH if product formulation is inadequate
- Requires careful formulation to ensure safe levels for consumer use
Science: The provided research discusses potassium hydroxide only as a laboratory diagnostic tool (KOH wet-mount preparation for fungal testing), not as an active skincare ingredient. Limited peer-reviewed data exists specifically on potassium hydroxide safety in cosmetic formulations at consumer-use concentrations. Safety depends entirely on proper dilution and formulation by manufacturers.
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Analysis not yet available for this ingredient.
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Turmeric root extract is a golden-colored ingredient derived from the turmeric plant, traditionally used in skincare for its anti-inflammatory and antioxidant properties. It contains curcumin, a compound believed to help calm irritated skin and protect against environmental damage.
Benefits
- May reduce redness and inflammation
- Antioxidant protection against free radicals
- Traditional use for uneven skin tone and radiance
Potential concerns
- May cause contact dermatitis or allergic reactions in sensitive individuals
- Can stain skin and clothing temporarily due to its yellow color
- Limited data on effectiveness at typical concentrations used in cosmetics
Science: Limited peer-reviewed data available for this ingredient at cosmetic-use concentrations. While turmeric has a long history in traditional medicine and some laboratory studies suggest anti-inflammatory potential, robust clinical evidence for skincare efficacy remains limited.
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Melia Azadirachta Flower Extract is derived from the neem tree flower and is used in skincare for its traditional antioxidant and soothing properties. It's typically included in formulations aimed at calming irritated skin and providing protective benefits.
Benefits
- Antioxidant protection
- May help soothe irritated skin
- Traditionally used in Ayurvedic skincare
Potential concerns
- Limited safety data in cosmetic use
- Potential for allergic reactions in sensitive individuals
- Quality and potency vary depending on extraction method
Science: Limited peer-reviewed data available for this ingredient in cosmetic formulations. Neem has a long history of use in traditional medicine, but specific safety and efficacy studies for the flower extract in skincare products are sparse.
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Melia Azadirachta Leaf Extract comes from neem leaves, a plant used in traditional medicine for centuries. In skincare, it's valued for its antimicrobial and anti-inflammatory properties, making it popular in products aimed at acne-prone or irritated skin.
Benefits
- May help reduce bacteria that contribute to acne
- Anti-inflammatory properties may soothe irritated skin
- Traditionally used to support skin clarity
Potential concerns
- Can cause contact dermatitis or allergic reactions in sensitive individuals
- Neem has a strong odor that some find unpleasant
- May increase sun sensitivity in some users
Science: Limited peer-reviewed data available for this ingredient in cosmetic formulations. Traditional use and in vitro studies suggest antimicrobial activity, but robust clinical evidence in skincare products remains limited.
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Corallina Officinalis Extract is a natural ingredient derived from red algae that contains antioxidants and antimicrobial compounds. In skincare, it's used to help protect skin from environmental damage and support the skin's natural defenses.
Benefits
- Antioxidant protection against free radicals and environmental stressors
- Antimicrobial properties that may help reduce problematic bacteria on skin
- Anti-inflammatory effects that may help calm irritated or reactive skin
- May support skin cell health and resilience
Potential concerns
- Limited safety data available for topical skincare use in humans
- Potential for allergic reaction in individuals sensitive to algae or iodine-containing ingredients
- May cause irritation in very sensitive or compromised skin barrier
Science: Research demonstrates strong antioxidant, antimicrobial, and anti-inflammatory activity in laboratory and wound-healing models, with good biocompatibility and low cytotoxicity observed. However, published data on this ingredient in cosmetic skincare formulations specifically for general consumers remains very limited.
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Ocimum Sanctum Leaf Extract, also known as Holy Basil, is a plant-derived ingredient traditionally used in South Asian medicine. In skincare, it's valued for its antioxidant and anti-inflammatory properties, which may help protect skin and soothe irritation.
Benefits
- Antioxidant protection against environmental stressors
- Anti-inflammatory properties that may help calm irritated skin
- Traditional use for treating skin conditions and inflammatory issues
Science: Research shows Ocimum sanctum leaf extract contains phytochemicals with antioxidant and antibacterial properties. Studies demonstrate its effectiveness in reducing oxidative stress and supporting skin health, though most peer-reviewed data focuses on nanoparticle synthesis and laboratory settings rather than direct skincare applications.
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Cellulose is a natural plant-derived polymer that acts as a thickener and structural support in skincare formulas. In skincare products like masks and serums, it forms a porous matrix that helps hold water and active ingredients on the skin, improving hydration and product delivery.
Benefits
- Increases skin hydration and moisture retention
- Improves product adhesion and allows for better delivery of active ingredients
- Biocompatible and well-tolerated by skin
- Supports the formation of masks and gel-like textures
Science: Research shows bacterial cellulose membranes significantly improve skin moisture, with one study demonstrating a 76% increase in hydration in most volunteers. Cellulose's highly porous nanostructure allows rapid incorporation and release of cosmetic actives, making it an effective support material for skincare applications.
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Glucomannan is a natural polysaccharide (a type of complex carbohydrate) extracted from plant sources like konjac root and found in aloe vera gel. In skincare, it acts as a humectant and thickening agent, helping to draw moisture into the skin and improve product texture.
Benefits
- Hydration support by attracting moisture to the skin
- Skin soothing and conditioning
- Helps improve product texture and spreadability
Potential concerns
- Allergic contact dermatitis possible in sensitive individuals, particularly if product contains aloe latex contamination
- May cause irritation in people with known sensitivities to polysaccharides
Science: Glucomannan is recognized as a safe polysaccharide component in topical skincare formulations. While direct cosmetic studies are limited, related polysaccharides show antioxidant and skin-protective properties; however, most published data focuses on glucomannan in oral supplements or aloe vera's multiple active compounds rather than glucomannan in isolation for skincare.
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Cetearyl Olivate is a natural emulsifier and skin-conditioning agent derived from olive oil. It helps blend oil and water-based ingredients together in skincare products while leaving skin feeling soft and moisturized.
Benefits
- Helps create smooth, stable product texture
- Provides light moisturizing properties
- Derived from natural olive oil
Science: Limited peer-reviewed data available for this ingredient. Cetearyl Olivate is widely used in cosmetics as a safe, naturally-derived emulsifier with a strong safety history in consumer skincare products.
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Sorbitan Olivate is an emulsifier derived from sorbitol (a natural sugar alcohol) and olive oil fatty acids. It helps mix oil and water-based ingredients together in skincare formulations, creating stable, smooth products.
Benefits
- Stabilizes product texture and prevents separation of oils and water
- Derived from natural olive oil, aligning with plant-based ingredient preferences
- Allows for creation of lighter, more elegant formulations
Potential concerns
- Generally mild skin irritant in some individuals; minimal irritation in most clinical studies
- Rare allergic contact dermatitis reported in fewer than 1% of sensitive individuals
- May cause greater irritation when combined with fragrance components
Science: The Cosmetic Ingredient Review Expert Panel concluded Sorbitan Olivate is safe for cosmetic use at concentrations typically below 10%. Clinical studies show it is generally a minimal to mild skin irritant and nonsensitizing in the general population, though rare allergic reactions have been documented in individuals with contact dermatitis.
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Avocado oil is a plant-based oil extracted from the fruit of the avocado tree. It's rich in fatty acids and vitamin E, making it a nourishing emollient that helps soften and hydrate the skin while improving the texture of skincare formulations.
Benefits
- Deep moisturization and skin softening
- Rich in antioxidants and vitamin E
- Helps improve skin barrier function
Potential concerns
- May cause comedogenic reactions in acne-prone individuals
- Possible allergic contact dermatitis in sensitive individuals
- Can leave a greasy residue if used in high concentrations
Science: Limited peer-reviewed data available for this ingredient. General knowledge suggests avocado oil is well-tolerated in cosmetic applications, though individual sensitivity varies depending on skin type and formulation concentration.
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Hydrogenated vegetable oil is a thickened plant-based oil made by adding hydrogen to vegetable oils, creating a solid or semi-solid texture. In skincare, it serves as an emollient and texture base that helps products feel smooth and creates a protective barrier on the skin.
Benefits
- Moisturizes and softens skin
- Creates a smooth, non-greasy product texture
- Acts as a natural alternative to mineral oil-based ingredients
Science: Hydrogenated vegetable oil is well-established as a safe cosmetic ingredient and food additive. Research shows it can effectively serve as a vehicle for delivering active ingredients to skin while being mild and non-irritating for topical use.
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Lauryl glucoside is a gentle, plant-derived surfactant (cleansing agent) made by combining a natural sugar with a fatty acid. It's commonly used in cleansers and shampoos to remove dirt and oil from skin while being milder than many synthetic alternatives.
Benefits
- Effective at cleansing without stripping skin
- Biodegradable and environmentally sustainable
- Gentler on skin compared to harsher surfactants
Potential concerns
- Can cause allergic contact dermatitis in sensitive individuals
- May cause irritation at high concentrations or with repeated exposure
Science: Lauryl glucoside is valued for its biodegradability and skin-gentleness in cosmetics. However, research shows it can trigger allergic contact reactions in some people, particularly those with existing sensitivities to similar surfactants like decyl glucoside.
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Disodium Laureth Sulfosuccinate is a mild, plant-derived cleansing agent (surfactant) that helps remove dirt and oil from skin. It's commonly used in gentle cleansers and is known for being less irritating than harsher surfactants.
Benefits
- Gentle cleansing that removes dirt and oil without stripping skin
- Low irritation potential, suitable for sensitive or compromised skin
- Effective in formulations designed to minimize hand eczema risk
Science: Research published in the International Journal of Cosmetic Science (2024) specifically evaluated this ingredient in combination with other mild surfactants and found it produced low irritation in patch testing while maintaining effective cleaning performance. The combination of disodium laureth sulfosuccinate with laureth-23 and cocamidopropyl betaine was noted as superior for both skin compatibility and cleansing efficacy.
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Soluble collagen is a protein derived from animal sources (commonly fish, bovine, or rabbit) that has been processed to dissolve easily in skincare formulations. It's used primarily as a hydrating and film-forming agent that temporarily plumps the skin surface and helps retain moisture.
Benefits
- Provides temporary hydration and plumping effect to skin
- Creates a smooth, moisturizing film on the skin surface
- May improve skin texture and appearance short-term
Potential concerns
- Topical collagen cannot penetrate skin or rebuild collagen in deeper layers despite marketing claims
- May cause sensitivity in those with shellfish or animal protein allergies depending on source
- Effects are temporary and wash off; does not provide lasting anti-aging benefits
Science: Research shows soluble collagen functions effectively as a hydrating and emulsifying agent in cosmetic formulations, with high protein content and good stability. However, scientific evidence does not support claims that topical collagen increases skin's own collagen production or penetrates dermis layers—its benefits are limited to surface-level moisturization and a temporary smoothing effect.
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Vanilla Planifolia Fruit Extract is derived from vanilla orchid pods and contains natural compounds like vanillin, polyphenols, and antioxidants. In skincare, it's primarily used for its antioxidant and soothing properties, and is valued for its pleasant scent and potential skin-conditioning benefits.
Benefits
- Antioxidant protection against environmental damage
- Soothing and calming properties for irritated skin
- Pleasant natural fragrance
Potential concerns
- Potential allergic reactions in sensitive individuals
- May cause contact dermatitis in rare cases
- Vanillin content could be irritating for very reactive skin types
Science: Limited peer-reviewed data available for this ingredient in skincare applications. Vanilla extract is generally recognized as safe (GRAS) for food use, and vanillin has demonstrated antioxidant properties in laboratory studies, but clinical efficacy data specific to topical skincare is minimal.
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Analysis not yet available for this ingredient.
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Lauric acid is a fatty acid naturally found in coconut oil that helps soften and condition the skin. In skincare products, it works to support the skin's natural barrier and can have mild antimicrobial properties.
Benefits
- May help prevent and treat atopic dermatitis (eczema)
- Supports skin barrier function
- Mild antimicrobial properties
Potential concerns
- May be comedogenic (pore-clogging) for acne-prone skin
- Can cause irritation in sensitive individuals
Science: Research shows consistent evidence supporting topical use for atopic dermatitis treatment and prevention. However, lauric acid behaves unpredictably in the body (both as a medium- and long-chain fatty acid), and most studies on coconut oil products show limited human clinical data—many findings are based on animal or lab studies rather than real-world use.
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