Dimethyl Isosorbide

Dimethyl Isosorbide

8.2

Ingredient Info

Dimethyl isosorbide is a clear liquid solvent derived from sorbitol that helps dissolve and deliver other skincare actives into the skin more effectively. It works by enhancing the penetration of beneficial ingredients and improving product texture and stability.



Benefits

  • Enhances penetration of active ingredients into skin
  • Improves product stability and shelf life
  • Lightweight solvent that feels comfortable on skin

Potential concerns

  • Can cause irritation or sensitization in sensitive skin at high concentrations
  • May increase skin penetration of other ingredients, which could be problematic if combined with irritating actives

Science: Dimethyl isosorbide is recognized as a penetration enhancer in cosmetic formulations. Research shows it has relatively low solubility for certain actives (such as piroctone olamine at 9.9 mg/mL), making it suitable for specific formulation strategies targeting epidermal delivery, though peer-reviewed safety and efficacy data in skincare is limited.



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